A new study has reopened the debate on artificial sweeteners, and some are saying it might actually cause obesity, not prevent it.

Sugars activate our reward circuits—they give us a hit of feel-good neurochemicals that prompt us to continue craving them. The more sugar you eat, the more you want it.

Since artificial sweeteners don’t satisfy your brain the way real sugar does, though, you don’t sate the craving. You’ll keep hankering after sweet foods and will probably end up eating more calories overall. That adds up to more pounds than you would’ve gained just by eating that cupcake in the first place.

Read more at Popular Science